Syllabus Entrance
Printer Friendly
Email Syllabus
Education Major Version

BI 417 Developmental Biology
Hoffman, Brian L.


Mission Statement: The mission of Park University, an entrepreneurial institution of learning, is to provide access to academic excellence, which will prepare learners to think critically, communicate effectively and engage in lifelong learning while serving a global community.

Vision Statement: Park University will be a renowned international leader in providing innovative educational opportunities for learners within the global society.

Course

BI 417 Developmental Biology

Semester

FA 2009 HO

Faculty

Hoffman, Brian L.

Title

Professor of Biology

Degrees/Certificates

BA Biology, Chemistry, Mathematics - Park College - 1986
PhD Cell and Molecular Biology - Saint Louis University - 1996

Office Location

SC 103

Office Hours

MTRF 10-11:30

Daytime Phone

584-6477

E-Mail

brian.hoffman@park.edu

Class Days

-M-W-F-  Laboratory R

Class Time

9:00-9:50 AM Laboratory 2:25-5:15 PM

Credit Hours

4


Textbook:

 

Required: Principles of Developmental Biology -- Fred Wilt and Sarah Hake
W.W. Norton and Company, 2003  ISBN 0-393-97430-8

Textbooks can be purchased through the MBS bookstore

Textbooks can be purchased through the Parkville Bookstore

Additional Resources:

McAfee Memorial Library - Online information, links, electronic databases and the Online catalog. Contact the library for further assistance via email or at 800-270-4347.
Career Counseling - The Career Development Center (CDC) provides services for all stages of career development.  The mission of the CDC is to provide the career planning tools to ensure a lifetime of career success.
Park Helpdesk - If you have forgotten your OPEN ID or Password, or need assistance with your PirateMail account, please email helpdesk@park.edu or call 800-927-3024
Resources for Current Students - A great place to look for all kinds of information http://www.park.edu/Current/.


Course Description:
A study of the molecular and cell biology of pattern formation in developing embryos. Systems surveyed include: Drosophila, sea urchin, frog, salamander, chicken and human. Prerequisites: BI231, CH317 and CH317L. 3:3:4

Learning Outcomes:
  Core Learning Outcomes

  1. Describe the basic landmark events in embryonic development.
  2. Describe the basic motifs of pattern formation during embryonic development.
  3. Relate the formation of specific structures in embryos to basic motifs of pattern formation.
  4. Describe the importance of developmental biology to understanding and reversing disease processes and birth defects.


Core Assessment:

Create a review paper in the style of Annual Reviews in Cell and Developmental Biology covering the development of one one structure (body axis, organ, appendage, segment polarity…etc.) This paper should be at least 10 pages in length (using the attached Instructions to Authors) excluding figures and references. Information covered should include:

1. Step-by-step illustration of the developmental or intercellular signaling pathway(s)  (i.e. inductive events, cell movements, localization of proteins or mRNAs in the embryo…etc) involved (CLO 1, 2, 3).

2. Discussion of the general flows of the pathway (flow of information, flow of mass, flow of energy) and the logic underlying the pathway (why does this arrangement work well?) (CLO 1, 2, 3).

3. Indication of key regulatory steps in the pathway and explanation of why this is a logical regulatory step (CLO 1, 2, 4).

4. Discuss the commonalities and differences exhibited in this pathway in different classes of animals (or plants) (CLO 4).

6. What diseases or disease states are associated with defects in this pathway? If there is no literature, predict what would happen (indicate your rationale) (CLO 1, 2, 4).

7. Discuss how the disease states in 6 are differentially expressed in human populations (is there a difference in disease effect or prevalence based on age, sex, geographic location, environmental factors, ancestral origin, race…etc). What are the bases of these differences? If there appears to be no difference in disease effect or prevalence, discuss why. (CLO 4)

8. Discuss methods used to combat the disease or approaches that are planned. How do/will these work? (CLO 4)

 

 

Link to Class Rubric

Class Assessment:

The teaching techniques utilized in this course include: traditional lectures by the instructor, small group discussions, and laboratory application of material learned in lecture. Student preparedness for lecture will be measured through the periodic administration of "pop" quizzes. The student's overall command of developmental biology will be measured with three regular examinations over lecture material. The examinations will be composed of short answer, matching and short essay problems.

Grading:

The grading scale for this class is:

100-90 = A (4.0 honor points)
89+-80 = B (3.0 honor points)
79+-70 = C (2.0 honor points)
69+-60 = D (1.0 honor point)
Below 60 = F (no honor points)

The following weight will be applied to all assignments:

Examination Average 55%
Laboratory Notebook 10%
Laboratory Reports 15%
Research Paper 20%

Late Submission of Course Materials:

Homework is due at the start of the assigned class period. Homework turned in after roll is taken is late. Late homework will be reduced in credit by 25% for each day or part of day that the work is late. Students missing class due to participation in athletic or other school-sponsored events must turn in all homework PRIOR to their absence. Exceptions: students who miss class due to an extended illness requiring hospitalization will be allowed to make up missed homework assignments. Other cases may be considered at the discretion of the instructor.

Classroom Rules of Conduct:

CLASSROOM RULES OF CONDUCT

A. Cellular Phones, Beepers, Other Communications Devices

While in class, the class should be your primary focus. Disruption of class due to communications devices has become so prevalent that they are a major distraction in class (to you, to the instructor and to other students). For this reason such devices must not be brought to class or must be inactivated during class (lecture and laboratory).

B. Student Alcohol or Drug Use

Because the classroom is a professional environment students who are suspected of being under the influence of alcohol or drugs will be removed from class. This also meets our legal obligation to provide a drug- and alcohol-free workplace. Such instances will be reported to the Vice-President for Academic Affairs. Students will not be admitted back into class unless such arrangements are made through the V.P. for Academic Affairs.

C. Student Work, Appointments...Etc.

The student who has signed up for the course has made an obligation to participate in those activities scheduled during regular class times. The student must not make other obligations during this time, or that student alone will be responsible for the consequences. The consequences may include reduced or no credit for that portion of the class and inability to make-up the missed work.

D. Withdrawals

The enrollment status of the student in this course is solely the responsibility of the student. If you wish to change your status in this course, be sure that you file the appropriate paperwork with the registrar before the appropriate deadlines. If you wish to drop, do not just stop coming to class!!! Two weeks of consecutive absences will result in your removal from the class. If you do not file withdrawal papers with the Registrar, you will receive an F in this course.

E. Extra Credit

It is your responsibility to get work done on time in an acceptable form. For this reason, no extra credit will be extended during the course of the semester.

F. Technology Issues

Computers make writing and revising much easier and more productive. Students must recognize though that technology can also cause problems. Printers run out of ink and hard drives crash. Students must be responsible for planning ahead and meeting deadlines in spite of technology. Be sure to save copies of your work to disk, hard drive, and print out paper copies for backup purposes. Papers will be submitted to the drop box in the eCompanion website for this course.

G. Make-Up Examinations

The student will be given the opportunity to make-up one examination during the course of the semester, provided that an adequate excuse is provided to the instructor within 24 hours of the missed examination. The instructor will be the final judge of what constitutes an adequate excuse. The makeup examination will be administered on Friday, December 14 at 8:00 AM and will be a cumulative final.

If you miss two exams, one will be scored as a zero and included in your examination average. Missing three examinations will result in a grade of "F" for the course. Four lecture examinations are scheduled for this semester. Your examination average will be calculated from all four test scores. If you feel that one test score is not representative of your effort, you may opt to take the make-up examination.  Failure to sit for the final examination will result in a grade of "F" for the course.

Exceptions:
athletes involved in sports contests or students participating in other school-sponsored events will be allowed to take the examination prior to the scheduled date. The instructor must be given prior notice of such an event.

DISABILITY GUIDELINES:   Park University is committed to meeting the needs of all students that meet the criteria for special assistance. These guidelines are designed to supply directions to students concerning the information necessary to accomplish this goal. It is Park University’s policy to comply fully with federal and state law, including Section 504 of the Rehabilitation Act of 1973 and the American with Disabilities Act of 1990, regarding students with disabilities and, to the extent of any inconsistency between these guidelines and federal and/or state law, the provisions of the law will apply. Additional information concerning Park University’s policies and procedures related to disability can be found on the Park University web page: http://www.park.edu/disability.

Course Topic/Dates/Assignments:

The following schedule is tentative and may be changed during the course of the semester.

Week
Topic (Chapter)
1
Basic Concepts (1)
2
Basic Concepts, Gametogenesis and Fertilization  (1,2)
3
Oogenesis, Pattern Formation,  Drosophila Body Plan (2,3)
4
Anamniote  and Amniote Body Plan (4, 5)
5
Mammal Body Plan and Vertebrate Ectodermal Derivatives (5,6)
6
Vertebrate Endodermal and Mesodermal Derivatives (6, 7)
7
Metamorphosis and Cell Differentiation (8, 9)
8
Cellular Associations, Environments and Behavior (12)
10
Tissue Associations (13)
11
Levels of Gene Expression in Development (14)
12
Developmental Regulatory Networks: Invertebrates (15)
13
Developmental Regulatory Networks: Vertebrates (16)
14
Plant Development (10)
15
Plant Development (11)
16
Plant Development (12)


Exam 1:  Week 6 Ch 1-5
Exam 2: Week 12  Ch 6-9, 12
Exam 3:  Week 17  The rest of it Ch 10-12, 13-16

Academic Honesty:
Academic integrity is the foundation of the academic community. Because each student has the primary responsibility for being academically honest, students are advised to read and understand all sections of this policy relating to standards of conduct and academic life.   Park University 2008-2009 Undergraduate Catalog Page 87

Plagiarism:
Plagiarism involves the use of quotations without quotation marks, the use of quotations without indication of the source, the use of another's idea without acknowledging the source, the submission of a paper, laboratory report, project, or class assignment (any portion of such) prepared by another person, or incorrect paraphrasing. Park University 2009-2010 Undergraduate Catalog Page 92

Attendance Policy:
Instructors are required to maintain attendance records and to report absences via the online attendance reporting system.

  1. The instructor may excuse absences for valid reasons, but missed work must be made up within the semester/term of enrollment.
  2. Work missed through unexcused absences must also be made up within the semester/term of enrollment, but unexcused absences may carry further penalties.
  3. In the event of two consecutive weeks of unexcused absences in a semester/term of enrollment, the student will be administratively withdrawn, resulting in a grade of "F".
  4. A "Contract for Incomplete" will not be issued to a student who has unexcused or excessive absences recorded for a course.
  5. Students receiving Military Tuition Assistance or Veterans Administration educational benefits must not exceed three unexcused absences in the semester/term of enrollment. Excessive absences will be reported to the appropriate agency and may result in a monetary penalty to the student.
  6. Report of a "F" grade (attendance or academic) resulting from excessive absence for those students who are receiving financial assistance from agencies not mentioned in item 5 above will be reported to the appropriate agency.

Park University 2009-2010 Undergraduate Catalog Page 95

Disability Guidelines:
Park University is committed to meeting the needs of all students that meet the criteria for special assistance. These guidelines are designed to supply directions to students concerning the information necessary to accomplish this goal. It is Park University's policy to comply fully with federal and state law, including Section 504 of the Rehabilitation Act of 1973 and the Americans with Disabilities Act of 1990, regarding students with disabilities. In the case of any inconsistency between these guidelines and federal and/or state law, the provisions of the law will apply. Additional information concerning Park University's policies and procedures related to disability can be found on the Park University web page: http://www.park.edu/disability .



Rubric

CompetencyExceeds Expectation (3)Meets Expectation (2)Does Not Meet Expectation (1)No Evidence (0)
Synthesis                                                                                                                                                                                                                                                  
Outcomes
1, 2 ,3, 4                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
Uses 7 or more sources Uses 4 to 6 sources Uses 3 to 5 sources Uses fewer than 3 sources 
Analysis                                                                                                                                                                                                                                                   
Outcomes
1, 2, 3, 4                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
Identifies and analyzes 7 or more of the items in the assignment Identifies and analyzes 4 to 6 of the items in the assignment Identifies and analyzes 3 to 5 of the items in the assignment Identifies and analyzes fewer than 3 of the items in the assignment 
Evaluation                                                                                                                                                                                                                                                 
Outcomes
1, 2, 3, 4                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
Assesses the outcomes of 7 or more of the assignment items Assesses the outcomes of 4 to 6 of the assignment items Assesses the outcomes of 3 to 5 of the assignment items Assesses the outcomes of  fewer than 3 of the assignment items 
Terminology                                                                                                                                                                                                                                                
Outcomes
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
No factual errors 1 to 2 factual errors 3 to 4 factual errors 5 or more factual errors 
Concepts                                                                                                                                                                                                                                                   
Outcomes
1, 2, 3, 4                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
Demonstrates mastery of 7 or more of the assignment items Demonstrates mastery of 4 to 6 of the assignment items Demonstrates mastery of 3 to 5 of the assignment items Demonstrates mastery of fewer than 3 of the assignment items 
Application                                                                                                                                                                                                                                                
Outcomes
1, 2, 3, 4                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           
Effectively incorporates 7 or more sources to support thesis Effectively incorporates 4 to 6 sources to support thesis Effectively incorporates 3 to 5 sources to support thesis Effectively incorporates fewer than 3 sources to support thesis 
Whole Artifact                                                                                                                                                                                                                                             
Outcomes
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
No errors in writing conventions 1 to 3 errors in writing conventions 4 to 6 errors in writing conventions 7 or more errors in writing conventions 
Component                                                                                                                                                                                                                                                  
Outcomes
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    
Contains no errors in the following paper format items: -Annual Review of Cell and Developmental Biology format –Length -Page numbers -Works cited -Internal documentation





 
Contains only 1 error in the following paper format items: -Annual Review of Cell and Developmental Biology format –Length -Page numbers-Works cited -Internal documentation





 
Contains 2 to 3 errors in the following paper format items: -Annual Review of Cell and Developmental Biology format –Length -Page numbers -Works cited -Internal documentation





 
Contains 4 or more errors in the following paper format items: -Annual Review of Cell and Developmental Biology format –Length -Page numbers -Works cited -Internal documentation





 
Relationship                                                                                                                                                                                                                                               
Outcomes
1,2,4                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                
Exhibits an awareness and concern for contemporary items Exhibits an awareness or concern for contemporary items Exhibits some awareness and concern for contemporary items Exhibits no awareness or concern for contemporary items 

Copyright:

This material is protected by copyright and can not be reused without author permission.

Last Updated:8/7/2009 8:11:15 PM