BI 337 Biochemistry
FA 2010 HO
Instructor of Biology
M.S. in Biochemistry and Molecular Biology, LSU Health Sciences Center
113A, Science Hall
M 9-10:00; T 8-10:00 & 2-3:00; W 9-11:00; R 9-10:00; F 8-9:00
August 16, 2010 - December 10, 2010
12:00 - 1:15 PM
CH318 and CH318L and/or the equivalent
Textbooks can be purchased through the MBS bookstore
Textbooks can be purchased through the Parkville Bookstore
McAfee Memorial Library - Online information, links, electronic databases and the Online catalog. Contact the library for further assistance via email or at 800-270-4347.Career Counseling - The Career Development Center (CDC) provides services for all stages of career development. The mission of the CDC is to provide the career planning tools to ensure a lifetime of career success.Park Helpdesk - If you have forgotten your OPEN ID or Password, or need assistance with your PirateMail account, please email email@example.com or call 800-927-3024Resources for Current Students - A great place to look for all kinds of information http://www.park.edu/Current/.
Educational Philosophy: Learning is an active and interactive process. Ideally, it would best be promoted by a combination of questioning and feedback involving each student. Thus, I like to teach in ways to try and reach all types of students with their diverse learning styles and do my best to provide a constructive learning environment. I like to enourage students to set high learning expectations, thus classroom attendance and participation are necessary for achievement of this goal.
Within the requirements of this course, the instructor will emphasize an organized interactive consideration of lecture material, readings, quizzes, projects, research papers, problem sets, examinations, internet websites, and similar exercises. Each student should strive to participate in class. In addition, course material will be applied and reinforced during laboratory exercises within the accompanying laboratory course; thus, it is an advantage to take both lecture and lab. Each student should expect to spend at least 3 hours of study outside of class for each credit hour of class.
Learning Outcomes: Core Learning Outcomes
Create a review paper in the style of Annual Reviews in Biochemistry covering one biochemical or intercellular signaling pathway in a cell or cells. This paper should be at least 10 pages in length (using the attached Instructions to Authors) excluding figures and references. Information covered should include:
1. Step-by-step illustration of the biochemical or intercellular signaling pathway (CLO 1, 2).
2. Discussion of the general flows of the pathway (flow of information, flow of mass, flow of energy) and the logic underlying the pathway (why does this arrangement work well?) (CLO 1,2, 3).
3. Indication of key regulatory steps in the pathway and explanation of why this is a logical regulatory step (CLO 1, 2, 4).
4. Indication of how this pathway relates to the central metabolic pathway (glycolysis, TCA cycle, electron transport chain, oxidative phosphorylation) (CLO 2).
5. Discuss the commonalities and differences exhibited in this pathway in prokaryotes and eukaryotes (CLO 4).
6. What diseases or disease states are associated with defects in this pathway? If there is no literature, predict what would happen (indicate your rationale) (CLO 1, 2, 4).
7. Discuss how the disease states in 6 are differentially expressed in human populations (is there a difference in disease effect or prevalence based on age, sex, geographic location, environmental factors, ancestral origin, race…etc). What are the bases of these differences? If there appears to be no difference in disease effect or prevalence, discuss why.
8. Discuss methods used to combat the disease or approaches that are planned. How do/will these work?
Link to Class RubricClass Assessment:
4 Exams (100 pts) 400 points
Final Exam 150 points
Homework/Quizzes 75 points
Review Paper 175 points
There will be 4 major lecture examinations worth 100 points each (400 total points). Exams will contain short answer, matching, multiple-choice, and a few discussion questions. Homework and announced quizzes will provide an additional 75 points of the final grade. The final exam will be worth 150 points. And finally, the review paper will be worth 175 points for a total of 800 total points possible.
Late Submission of Course Materials: Late homework and assignments (including lab notebooks when called in for review or lab projects with a dated deadline) will be reduced in credit by 25% for each day that the work is late. Students missing class due to participation in athletic or other university-sponsored events must turn in all due assignments PRIOR to their expected absence.
No makeup exams or quizzes will be given unless proper documentation of the reason for the absence is provided. Only SERIOUS incidences will even be considered. Make up exams will be given only at the instructors discretion.
Classroom Rules of Conduct:
Week of 8/16
Introduction, Bonds, Amino Acids
1, 2, 3
Week of 8/23
Carbohydrates, Lipids, Protein Structure
9, 10, 4
Week of 8/30
Enzymes – Action/ Regulation/ Mechanisms & Inhibitors
5, 6, 7
Week of 9/6
Labor Day Holiday, Enzymes – Mechanisms & Inhibitors, Allosteric Proteins
Week of 9/13
EXAM I, Membrane Structure & Function
11 (EI – 1-5, 9, 10)
Week of 9/20
Signal Transduction, Introduction to Metabolism
Week of 9/27
Digestion, Glycolysis I
Week of 10/4
Glycolysis II, EXAM II
15 (EII – 6-8, 11, 12)
Week of 10/11
FALL BREAK – NO CLASSES
Week of 10/18
Gluconeogenesis, Preparation for the Citric Acid Cycle
Week of 10/25
Citric Acid Cycle II, Electron Transport Chain
Week of 11/1
EXAM III, Oxidative Phosphorylation
20 (EIII – 13-18)
Week of 11/8
Glycogen Degradation/Synthesis, Glucose homeostasis & Disease
Week of 11/15
Lipid/Fatty Acid Degradation, Lipid/Fatty Acid Synthesis
Week of 11/22
EXAM IV, Lipid Storage
28 (EIV – 19,20,23,24,26)
Week of 11/29
Molecular Biology Overview
ALL TERM PAPERS DUE BY 12/03/10
Week of 12/6
FINAL EXAM (EXAM V) - Monday Dec. 6 – 1:00-3:00
Academic Honesty:Academic integrity is the foundation of the academic community. Because each student has the primary responsibility for being academically honest, students are advised to read and understand all sections of this policy relating to standards of conduct and academic life. Park University students and faculty members are encouraged to take advantage of the University resources available for learning about academic honesty (www.park.edu/current or http://www.park.edu/faculty/).from Park University 2010-2011 Undergraduate Catalog Page 92
Plagiarism:Plagiarism involves the use of quotations without quotation marks, the use of quotations without indication of the source, the use of another's idea without acknowledging the source, the submission of a paper, laboratory report, project, or class assignment (any portion of such) prepared by another person, or incorrect paraphrasing. from Park University 2010-2011 Undergraduate Catalog Page 92-93
Attendance Policy:Instructors are required to maintain attendance records and to report absences via the online attendance reporting system.
Park University 2010-2011 Undergraduate Catalog Page 95-96
Disability Guidelines:Park University is committed to meeting the needs of all students that meet the criteria for special assistance. These guidelines are designed to supply directions to students concerning the information necessary to accomplish this goal. It is Park University's policy to comply fully with federal and state law, including Section 504 of the Rehabilitation Act of 1973 and the Americans with Disabilities Act of 1990, regarding students with disabilities. In the case of any inconsistency between these guidelines and federal and/or state law, the provisions of the law will apply. Additional information concerning Park University's policies and procedures related to disability can be found on the Park University web page: http://www.park.edu/disability .
Last Updated:8/10/2010 3:15:21 PM